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As Climate Disasters Increase, Official Responses Like FEMA to Helene Come Up Short

As Climate Disasters Increase, Official Responses Like FEMA to Helene Come Up Short

We’ve repeatedly chronicled increasingly visible and consequential examples of failures in organizational capabilities. The degree of institutional brain rot has become disconcertingly visible in recent years, particularly among top national officials and international institutions (we’re looking at you, Ursula). These shortcomings are set to become a critical lapse as climate change related disasters become more … Read more

Healthy brains suppress inappropriate immune responses

Healthy brains suppress inappropriate immune responses

The brain constantly engages in dialogue with the body’s immune system. Such communication appears aimed at ensuring a delicate balance between defending against injury and infection and guarding healthy tissue. Now, scientists at Washington University School of Medicine in St. Louis have revealed how the two strike a healthy balance. The study, in mice, found … Read more

An individual’s reward-seeking strategy reflects responses to nicotine

An individual’s reward-seeking strategy reflects responses to nicotine

Individualistic reward-seeking strategies predict responses to nicotine among mice living in a micro-society, according to a study publishing October 24 in the open-access journal PLOS Biology by Philippe Faure from PSL Research University, France, and colleagues. Individual animals differ in their traits and preferences, which shape their social interactions, survival, and susceptibility to disease, including … Read more

Maternal antibodies interfere with malaria vaccine responses

Maternal antibodies interfere with malaria vaccine responses

Maternal antibodies passed across the placenta can interfere with the response to the malaria vaccine, which would explain its lower efficacy in infants under five months of age, according to research led by the Barcelona Institute for Global Health (ISGlobal), in collaboration with seven African centers (CISM-Mozambique, IHI-Tanzania, CRUN-Burkina Faso, KHRC-Ghana, NNIMR-Ghana, CERMEL-Gabon, KEMRI-Kenya). The … Read more