RNA sequencing approach offers real-time and programmable transcriptome sequencing

RNA sequencing approach offers real-time and programmable transcriptome sequencing

Real-time and programmable transcriptome sequencing with PROFIT-seq. Credit: Nature Cell Biology (2024). DOI: 10.1038/s41556-024-01537-1 The high complexity and diversity of the eukaryotic transcriptome poses significant challenges for the efficient detection of specific transcripts. Conventional targeted RNA-seq methods often require labor-intensive pre-sequencing enrichment steps, which can compromise comprehensive transcriptome profiling and limit their broader applications. Recently, … Read more