Groundbreaking research unlocks precision therapy for drug-resistant leukaemia

Groundbreaking research unlocks precision therapy for drug-resistant leukaemia

Scientists from Duke-NUS Medical School and their collaborators have identified an inherited genetic variation prevalent among East Asians that contributes to drug resistance, driving the aggressive growth of cancer cells in patients with chronic myeloid leukaemia. To address this, the team’s pioneering approach involves inhibiting the action of a protein called MCL-1, with laboratory studies … Read more